A scientific study by specialists from the MARTINEX International Research and Development Center for Innovative Technologies has been published in "Medical Alphabet" , a leading Russian medical publication (No. 23, 2025, Dermatology section).
The article, led by PhD in Medical Sciences Mikhaylova Natalia Pavlovna, Scientific Director of MARTINEX, is dedicated to modern understanding of hyaluronic acid as a key biopolymer for correcting age-related skin changes.
The paper, titled "Hyaluronic acid in the correction of age-related skin changes: optimal physico-chemical characteristics, modifications, and personalized strategies," reveals the principles determining the effectiveness of hyaluronic acid in injection therapy. The research details such critically important parameters as molecular weight, polymer structure, interaction with cellular receptors, and substance stabilization pathways.
The publication pays special attention to the innovative technology of solid-phase modification of hyaluronic acid. This method excludes the use of toxic reagents and enables the creation of products that combine volumetric correction with targeted biochemical action on the skin's extracellular matrix.
This approach opens a new direction in product development: from traditional fillers to personalized bio-regulatory systems capable of not just adding volume but also restoring the skin's own structure.
"Today, it is important not merely to replenish volume deficit but to address the causes of age-related changes," commented PhD in Medical Sciences Mikhaylova Natalia Pavlovna, Scientific Director of MARTINEX. "Managing the parameters of hyaluronic acid allows us to create products that work with the skin as a living system—gently, safely, and physiologically."
The publication in the leading specialized journal confirms the high level of scientific expertise of MARTINEX ANO IRCIT and underscores its contribution to the development of evidence-based injection cosmetology. Each new work by the research team strengthens the position of the HYALREPAIR® brand as the pioneer of Russian bioreparation technologies, which continues to shape standards in the field of anti-age therapy.